Long-term preservation of planar cell polarity in reversed tracheal epithelium
نویسندگان
چکیده
منابع مشابه
Long-term preservation of planar cell polarity in reversed tracheal epithelium
BACKGROUND Planar cell polarity (PCP) coordinates the patterning and orientation of cells and their structures along tissue planes, and although its acquisition during the formation of airway epithelium has been described, the mechanisms for its maintenance and reconstruction are poorly understood. We aimed to clarify whether ambient environment change by orthotropic autologous transplantation ...
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In all multicellular organisms, epithelial cells are not only polarized along the apical-basal axis, but also within the epithelial plane, giving cells a sense of direction. Planar cell polarity (PCP) signaling regulates establishment of polarity within the plane of an epithelium. The outcomes of PCP signaling are diverse and include the determination of cell fates, the generation of asymmetric...
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The planar cell polarity (PCP) pathway regulates morphogenesis in various organs. The polarized localization is a key feature of core PCP factors for orchestrating cell polarity in an epithelial sheet. Several studies using Drosophila melanogaster have investigated the mechanism of the polarized localization. However, to what extent these mechanisms are conserved and how the polarization of cor...
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2018
ISSN: 1465-993X
DOI: 10.1186/s12931-018-0726-y